High Desert Health, LLC
Tributyrin-Max
Tributyrin-Max
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Postbiotic Colon and Microbiome Support*
60, 750 mg tributyrin capsules
Free shipping for 1-3 bottles.
SUPPORTS HEALTHY DIGESTIVE TRANSIT - If food passes through your digestive system too quickly and leads to loose stool, tributyrin is an ideal choice. Tributyrin-Max may help firm up bowel movements and decrease bloating.* Tributyrin is the superior, slow-release form of butyrate, a short chain fatty acid (also known as a postbiotic) produced when a healthy gut microbiome ferments fiber. May support the gut microbiome when impacted by antimicrobials, which decrease the natural ability of the gut microbiome to produce butyrate.*
SUPPORTS A HEALTHY GUT MICROBIOME AND GUT LINING INTEGRITY – By feeding the cells lining the colon, Tributyrin-Max helps maintain the integrity of the lining of the colon, encouraging the growth of butyrate-producing anaerobic bacteria.* This in turn may decrease food sensitivities and histamine reactions.*
MODERATES VISCERAL SENSITIVITY AND SUPPORTS A BALANCED IMMUNE RESPONSE – Decreases sensitivity to digestive pain and discomfort.* Supports the formation of regulatory T-cells, which support a balanced inflammatory response.*
HIGHEST DOSE CAPSULE – At 60 capsules of 750 mg, Tributyrin-Max is one of the highest-dose tributyrin capsules currently available, requiring fewer pills to achieve an effective dose.
ENTERIC CAPSULE – Tributyrin-Max contains 750 mg of tributyrin powder in a plant-based, enteric capsule for delivery through the stomach acid to your intestines. Non-GMO, third-party tested gluten-free and dairy-free and brought to you by the host of The Perfect Stool podcast.
Butyrate (of which tributyrin is the superior form) is a well-studied but relatively new and not well-known supplement.
Some of the impacts of butyrate in the gastrointestinal tract, established by peer-reviewed research, which can be of help to sufferers of IBS-D or irritable bowel syndrome with diarrhea (or loose stool) include:
- Slowing intestinal motility,1 meaning more water absorbed, so harder stools with a clean wipe
- Decreasing inflammation2
- Moderating visceral sensitivity meaning decreased sensitivity to pain in the internal organs
- Increasing gut hypoxia and helping seal a leaky gut (by removing oxygen that favors inflammatory bacteria)3 which may in turn decrease food sensitivities and histamine reactions
Research has also confirmed its benefits beyond the gut:
- Immune Health: Supports balanced immune responses4
- Metabolic Health: Supports stable energy and healthy glucose levels5
Why is Tributyrin better than other forms of butyrate?
The Tributyrin form of butyrate (as opposed to sodium butyrate, potassium butyrate, magnesium butyrate or calcium butyrate forms) is superior because of low odor, chemical stability, rapid absorption in plasma, and ability to diffuse through biological membranes, releasing butyrate over time directly into cells as opposed to butyrate, which is metabolized rapidly as soon as it enters the cells lining the colon.
What is butyrate?
Butyrate is a form of butyric acid, which is a short chain fatty acid (SCFA) that is created through the fermentation of fiber in our colon by beneficial bacteria. It feeds the colonocytes, or cells lining the colon. Metabolism of butyrate by the colonocytes is responsible for more than 70% of oxygen consumption, which means its presence helps maintain an anaerobic environment in the gut, favorable to anaerobic bacteria that promote a healthy gut barrier and continued production of butyrate7. In animal models, three days of oral antibiotics dramatically decreased butyrate production and increased oxygen levels in the gut. This promotes the growth of facultative anaerobic bacteria (or bacteria that can live with or without the presence of oxygen), typically proteobacteria, leading to loose stool and an influx of oxygen, which further increases the presence of proteobacteria. This leads to an inflamed and leaky colon. Supplemental butyrate may help reverse this cycle and restore the colon to a healthy balance of anaerobic and facultative anaerobic bacteria.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
1. Canani, RB et al. Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J Gastroenterol. 2011 Mar 28; 17(12): 1519–1528. doi:10.3748/wjg.v17.i12.1519
2. Siddiqui MT, Cresci GAM. The Immunomodulatory Functions of Butyrate. J Inflamm Res. 2021;14: 6025–6041. doi:10.2147/JIR.S300989
3. Kelly CJ et al. Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function. Cell Host Microbe. 2015;17: 662–671. doi: 10.1016/j.chom.2015.03.005
4. Takahashi, D et al. Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells. EBioMedicine. 2020; 58: 102913. doi:10.1016/j.ebiom.2020.102913
5. Arora T & Tremaroli V. Therapeutic Potential of Butyrate for Treatment of Type 2 Diabetes. Front Endocrinol. 2021;12: 761834. doi: 10.3389/fendo.2021.761834
6. Coppola S, Avagliano C, Calignano A, Berni Canani R. The Protective Role of Butyrate against Obesity and Obesity-Related Diseases. Molecules. 2021;26. doi: 10.3390/molecules26030682
7. Mailing, L. (2019). The Oxygen Gut Dysbiosis Connection. https://www.lucymailing.com/the-oxygen-gut-dysbiosis-connection/
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Let customers speak for us
from 8 reviewsAt this time have not taken it. I am in the process of trying various ones. I know the Tributyrin works, because Dr. Gundry's original formula which had a 1000 gr worked, but he change his formula to 300 and that is not working for me. I had bought various bottles of his product. I am taking 3 pills of Dr. Gundry to equal 450 gr plus another supplier that had over 500 gr to equal my 1000. Five days on that changed my issue. So very frustrated the formulas were changed. No updated info on why? So the search was on and also concern with not obeying the bottle recommendations.
This product has been a life changer.
I found it important (for me) to take 2-3 full doses per day.
I have gone from uncontrolled diarrhea for years to perfectly formed stools today. All in less than a month.
Tributyrin-Max has been a game changer for me in helping to heal my leaky gut. I'm finally beginning to feel improvements throughout my entire body. I have less inflammation, and I am continuing to seeing gradual improvements In my gut motility. I will definitely continue to use this product!
I started Tributyrin-MAX due to loose stool, especially during frequent juicing and fruit and vegetable smoothies. This pill was a miracle. Immediately the next day, I noticed the difference in firm bowel movements. In three days, the effect was full. I could not be happier. I highly recommend the product.
I have been taking this for more than three weeks and when I was just taking 1 or 2 a day i didnt see much difference but once I got up to three a day my bowel movements really improved and were well formed. And I seem much more able to tolerate a diversity of foods.
I can’t believe how much better I feel thank your so much
Tributyrin-Max
While apparently the majority of stool dysfunction is hard stools, I've always h had loose stools. This is the only thing that I can use to routinely firm them up, so that my gut can heal.